Production of recombinant proteins in serum-free media

@article{Broad1991ProductionOR,
  title={Production of recombinant proteins in serum-free media},
  author={David F Broad and R. C. Boraston and Mitchell L. Rhodes},
  journal={Cytotechnology},
  year={1991},
  volume={5},
  pages={47-55}
}
The advantages of serum-free culture for the manufacture of recombinant biopharmaceuticals from mammalian cells are reviewed. The process favoured is fed-batch serum-free cell culture. This process is applicable to the majority of cell lines, is practical on the large scale, gives the lowest manufacturing cost, and can b e carried out without the use of any serum. The advantages of serum-free culture for the manufacture of recombinant biopharmaceuticals from mammalian cells are reviewed. The… CONTINUE READING

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