Production of proinflammatory cytokines and myocardial dysfunction after arterial switch operation in neonates with transposition of the great arteries.

@article{HvelsGrich2002ProductionOP,
  title={Production of proinflammatory cytokines and myocardial dysfunction after arterial switch operation in neonates with transposition of the great arteries.},
  author={Hedwig Hubertine H{\"o}vels-G{\"u}rich and Jaime Francisco Vazquez-Jimenez and Anna Silvestri and Kathrin Schumacher and Ralf Minkenberg and Jean Duchateau and Bruno J. Messmer and G von Bernuth and M Seghaye},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2002},
  volume={124 4},
  pages={811-20}
}
OBJECTIVE Neonates undergoing cardiac surgery have a systemic inflammatory reaction with release of proinflammatory cytokines, which could be responsible for myocardial dysfunction as a result of myocardial cell damage. The purpose of this study was to test the hypothesis that the production of proinflammatory cytokines during cardiac surgery would be associated with myocardial dysfunction after the arterial switch operation in neonates. METHODS A total of 63 neonates with transposition of… CONTINUE READING
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