Production of platelet-activating factor by chick retina.

  title={Production of platelet-activating factor by chick retina.},
  author={Federico Bussolino and Fulvia Gremo and Ciro Tetta and Gian Piero Pescarmona and Giovanni Camussi},
  journal={The Journal of biological chemistry},
  volume={261 35},
In the present study it is demonstrated that platelet-activating factor (PAF) was produced by chick retinas, upon stimulation with neurotransmitters such as acetylcholine (ACh), dopamine, or with calcium ionophore A23187, but not upon stimulation with gamma-amino-n-butyric acid, L-glycine, L-glutamate, epinephrine, or histamine. PAF produced in response to ACh, dopamine, or A23187 was not released into supernatants but was extractable from retinas. The amounts of extractable PAF increased after… CONTINUE READING


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