Production of oxidative products of nitric oxide in infarcted human heart.

  title={Production of oxidative products of nitric oxide in infarcted human heart.},
  author={Kazuhide Akiyama and Akinori Kimura and Hidekazu Suzuki and Youichi Takeyama and Tracy L Gluckman and Artin Terhakopian and Takashi Katagiri and Kahp Y. Suh and J Roseto and Richard J. Bing},
  journal={Journal of the American College of Cardiology},
  volume={32 2},
OBJECTIVES We sought to assess whether oxidation products of nitric oxide (NO), nitrite (NO2-) and nitrate (NO3-), referred to as NOx, are released by the heart of patients after acute myocardial infarction (AMI) and whether NOx can be determined in peripheral blood of these patients. BACKGROUND Previously we reported that in experimental myocardial infarction (rabbits) NOx is released mainly by inflammatory cells (macrophages) in the myocardium 3 days after onset of ischemia. NOx is formed… CONTINUE READING


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