Corpus ID: 20111296

Production of interleukin-2 by mononuclear cells in vitro in patients with atopic dermatitis and psoriasis. Comparison with serum interleukin-2 receptor levels.

@article{Kapp1991ProductionOI,
  title={Production of interleukin-2 by mononuclear cells in vitro in patients with atopic dermatitis and psoriasis. Comparison with serum interleukin-2 receptor levels.},
  author={Alexander Kapp and Peter Neuner and Jean Krutmann and Thomas Anton Luger and Erwin Schoepf},
  journal={Acta dermato-venereologica},
  year={1991},
  volume={71 5},
  pages={
          403-6
        }
}
  • Alexander Kapp, Peter Neuner, +2 authors Erwin Schoepf
  • Published in Acta dermato-venereologica 1991
  • Medicine
  • Atopic dermatitis is associated with profound immunological alterations, in particular decreased lymphoproliferative responses upon stimulation with T-cell mitogens. T-cell blastogenesis involves the production of the soluble cytokine interleukin-2 (IL-2), which in turn upregulates the expression of its own receptor. To investigate the potential role of this cytokine for the pathomechanisms present in atopic dermatitis, 24-h supernatants of PHA-stimulated peripheral blood mononuclear cells from… CONTINUE READING

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