Production of interferon in mice: effect of altered gaseous environments.

Effects of altered gaseous environments (parabarosis) on interferon production in mice were studied, with Newcastle disease virus (NDV) as the inducer. Increased levels of interferon in lung tissue were observed when mice were exposed to 11% O(2) in N(2) for 3 days before and after, or only after, injection of NDV. However, serum interferon levels remained… CONTINUE READING