• Medicine
  • Published in
    Journal of interferon…
    1995

Production of interferon-gamma by chicken T cells.

@article{Lowenthal1995ProductionOI,
  title={Production of interferon-gamma by chicken T cells.},
  author={John W. Lowenthal and Matthew Robert Digby and John J. York},
  journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research},
  year={1995},
  volume={15 11},
  pages={
          933-8
        }
}
In mammals, interferon (IFN)-alpha/beta (type I) is typically resistant to exposure to heat and low pH, whereas IFN-gamma (type II) is labile. Type I IFN has been described in birds; however, the existence of type II IFN has been questioned. We have generated cloned chicken T cell lines that produce high levels of IFN and have studied the physiochemical properties of this IFN activity to determine whether it represents the type I or type II IFN found in mammals. When incubated at 60 degrees C… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

Cloning and expression of pigeon IFN-γ gene.

  • Research in veterinary science
  • 2010
VIEW 5 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Small interfering RNA-mediated knockdown of chicken interferon-γ expression.

  • Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
  • 2013