Production of interferon and of virus-neutralizing antibodies in adult mice infected with enteroviruses in the neonatal period

Abstract

Newborn albino mice were infected with three strains of enteroviruses and reinfected 6 weeks later with homologous or heterologous strains. Strains with relatively low pathogenicity for newborn mice were shown to lead to the formation of specific immunologic memory. If virus of high pathogenicity was used, prolonged production of specific antiviral… (More)
DOI: 10.1007/BF00801350

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