Corpus ID: 28197458

Production of immunogenic human papillomavirus-16 major capsid protein derived virus like particles.

@article{Patel2009ProductionOI,
  title={Production of immunogenic human papillomavirus-16 major capsid protein derived virus like particles.},
  author={Mira C. Patel and Ketaki Patkar and Atanu Basu and Kunissery Mallath Mohandas and Robin Mukhopadhyaya},
  journal={The Indian journal of medical research},
  year={2009},
  volume={130 3},
  pages={
          213-8
        }
}
  • Mira C. Patel, Ketaki Patkar, +2 authors Robin Mukhopadhyaya
  • Published in
    The Indian journal of medical…
    2009
  • Medicine
  • BACKGROUND & OBJECTIVE Recombinant DNA technology allows expression of the human papillomavirus (HPV) major capsid protein (L1) in heterologous expression systems and the recombinant protein self assembles to virus-like particles (VLP). We took up this study to produce recombinant HPV-16 L1 in yeast, establish the process of recombinant L1 derived VLP preparation and develop an ELISA using VLP as the antigen for serological evaluation of anti HPV-16 L1 antibody status. METHODS Complete HPV-16… CONTINUE READING

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