[Production of human proteins in the blood of transgenic animals].


The human alpha 1-antitrypsin gene has been microinjected into rabbit embryos. A line of transgenic rabbits has thus been established. Human alpha 1-antitrypsin was found in the blood of transgenic animals at the concentration of 1 mg/ml plasma. The human protein was active and separable from its rabbit counterpart. This experiment demonstrates that it is… (More)


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@article{Massoud1990ProductionOH, title={[Production of human proteins in the blood of transgenic animals].}, author={Mahmoud Massoud and Ralf F Bischoff and W Dalemans and Herv{\'e} Pointu and Jo{\'e} Attal and Huguette Schultz and Daniel Clesse and Marie-georges Stinnakre and Andrea Pavirani and Louis Marie Houdebine}, journal={Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie}, year={1990}, volume={311 8}, pages={275-80} }