Production of human alpha 1-antichymotrypsin-like protein by a human malignant melanoma transplanted into nude mice.

@article{Kondo1982ProductionOH,
  title={Production of human alpha 1-antichymotrypsin-like protein by a human malignant melanoma transplanted into nude mice.},
  author={Yutaka Kondo and Nakaaki Ohsawa},
  journal={Cancer research},
  year={1982},
  volume={42 4},
  pages={1549-54}
}
A tissue culture line of a human malignant melanoma, SEKI, induced cachexia in nude mice (BALB/c-nu/nu) (Kondo et al., Cancer Res., 41: 2912-2916, 1981). During the investigation of the cause of the cachexia, the melanoma was found to produce a protein immunologically identical to human alpha 1-antichymotrypsin (alpha 1-Ach). Tissues of the SEKI melanoma… CONTINUE READING