Production of granulocyte-macrophage colony-stimulating factor in a patient with metastatic chest wall large cell carcinoma.

@article{Watanabe1998ProductionOG,
  title={Production of granulocyte-macrophage colony-stimulating factor in a patient with metastatic chest wall large cell carcinoma.},
  author={Masazumi Watanabe and Koji Ono and Yuichi Ozeki and Sachiko Tanaka and Shinsuke Aida and Yoshiaki Okuno},
  journal={Japanese journal of clinical oncology},
  year={1998},
  volume={28 9},
  pages={559-62}
}
Recent reports of cancers that produce colony-stimulating factors (CSF) and which are associated with leukocytosis indicate that most are granulocyte CSF-producing tumors. A 71-year-old man with metastatic chest wall tumors from large cell lung cancer with marked leukocytosis and eosinophilia was reported. His maximal leukocyte count was 48300/microliter with 37.5% eosinophils. Granulocyte-macrophage CSF (GM-CSF) activity detected by enzyme-linked immunosorbent assay (ELISA) in serum was 112 pg… CONTINUE READING
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