Production of ergot alkaloids in vitro by Sphacelia sorghi.

  title={Production of ergot alkaloids in vitro by Sphacelia sorghi.},
  author={Peter Gregory Mantle},
  journal={Journal of general microbiology},
  volume={75 2},
SUMMARY: A method is described for the production of dihydrogenated ergot alkaloids, principally dihydroergosine, in yields exceeding 0.5 mg/ml in surface liquid cultures of Sphacelia sorghi. Alkaloid production occurred at the end of the growth phase and most of the product was released into the medium. An increase in the proportion of unsaturated fatty acids in the mycelial triglyceride oils during the growth phase was associated with the development of sclerotium-like tissues within the… CONTINUE READING

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