Production of ectoine through a combined process that uses both growing and resting cells of Halomonas salina DSM 5928T

@article{Lang2011ProductionOE,
  title={Production of ectoine through a combined process that uses both growing and resting cells of Halomonas salina DSM 5928T},
  author={Ya-jun Lang and Lin Bai and Ya-Nan Ren and Linghua Zhang and Shinichi Nagata},
  journal={Extremophiles},
  year={2011},
  volume={15},
  pages={303-310}
}
Using ectoine-excreting strain Halomonas salina DSM 5928T, we developed a new process for high-efficiency production of ectoine, which involved a combined process of batch fermentation by growing cells and production by resting cells. In the first stage, batch fermentation was carried out using growing cells under optimal fermentation conditions. The second stage was the production phase, in which ectoine was synthesized and excreted by phosphate-limited resting cells. Optimal conditions for… CONTINUE READING

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