Production of cyclic GMP via activation of B1 and B2 kinin receptors in cultured bovine aortic endothelial cells.


The purpose of this study was to define the type of kinin receptors in bovine aortic endothelial cells. As a biochemical response we used the cyclic GMP production which can be attributed to the activation of the soluble guanylyl cyclase of the endothelial cells via endothelium-derived relaxing factor. For the first time we demonstrated that in addition to… (More)


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