Production of canthin-6-one alkaloids by cell suspension cultures of Brucea javanica (L.) Merr.

@article{Liu1990ProductionOC,
  title={Production of canthin-6-one alkaloids by cell suspension cultures of Brucea javanica (L.) Merr.},
  author={Karin C. -S. Liu and Shilin Yang and Margaret F. Roberts and J. David Phillipson},
  journal={Plant Cell Reports},
  year={1990},
  volume={9},
  pages={261-263}
}
Cell suspension cultures of Brucea javanica (L.) Merr. were used to determine culture growth characteristics and production of canthin-6-one alkaloids. The major alkaloids produced were canthin-6-one, 11-hydroxycanthin-6-one, 5-methoxycanthin-6-one and 11-methoxycanthin-6-one. Alkaloids were synthesised throughout the 36 day growth cycle of the cells with maximum amounts within the cells occurring between days 20 to 28; approximately 10% of the alkaloids were in the medium at day 24 rising to… CONTINUE READING

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