Production of bioavailable flavonoid glucosides in fruit juices and green tea by use of fungal alpha-L-rhamnosidases.

@article{GonzlezBarrio2004ProductionOB,
  title={Production of bioavailable flavonoid glucosides in fruit juices and green tea by use of fungal alpha-L-rhamnosidases.},
  author={Roc{\'i}o Gonz{\'a}lez-Barrio and Luisa M Trindade and Paloma Manzanares and Leo H. de Graaff and Francisco A. Tom{\'a}s-Barber{\'a}n and Juan Carlos Esp{\'i}n},
  journal={Journal of agricultural and food chemistry},
  year={2004},
  volume={52 20},
  pages={
          6136-42
        }
}
Flavonoid glucosides have been reported to be more bioavailable than their rutinoside counterparts. The aim of this study is to describe a first step in the use of alpha-L-rhamnosidases (RhaA and RhaB) from Aspergillus aculeatus as a way to produce functional beverages based on their potentially increased flavonoid bioavailability. Blackcurrant juice (BCJ), orange juice (OJ), and green tea infusion (GT) were incubated with either RhaA or RhaB at 30 degrees C for 10 h. Aliquots of controls and… Expand
Enhancement of the antioxidant activity of orange and lime juices by flavonoid enzymatic de-glycosylation
Abstract Pure flavonoid glycosides and those present in orange ( Citrus sinensis ) and lime ( Citrus latifolia ) juices were structurally modified by enzymatic de-glycosylation to obtain functionalExpand
Optimization of the production of α-L-rhamnosidase by Aspergillus niger in solid state fermentation using agro-industrial residues.
ABSTRACT The enzyme α-L-rhamnosidase specifically cleaves terminal rhamnose residues from awide variety of natural products. This property endows this enzyme with importantbiotechnological potentialExpand
Bioconversion of Cyanidin-3-Rutinoside to Cyanidin-3-Glucoside in Black Raspberry by Crude α-L-Rhamnosidase from Aspergillus Species.
TLDR
To enhance the bioavailability of anthocyanins in black raspberry by cleaving L-rhamnose in C3R using crude enzyme extracts from Aspergillus usamii, A. awamori and A. niger, the enzyme activities of the CEEs were determined by a spectrophotometric method. Expand
DEGRADATION OF FLAVONOIDS BY Cryptococcus albidus α-L-RHAMNOSIDASE
TLDR
The strong interest to -L-rhamnosidase is caused exactly by its ability to split off the terminal rhamnose, thus opening a wide field of possible applications of the enzyme for biodegradation of flavonoids. Expand
Analysis of phenolic compounds in Portuguese wild and commercial berries after multienzyme hydrolysis.
TLDR
This method is able to disclose new sources of dietary phenolic compounds, and the potential usefulness of Portuguese crowberry and strawberry tree fruit is shown to be a simple alternative to other existing methods for analysis of plant phenolic compound aglycones. Expand
Synthesis of quercetin-3-O-glucoside from rutin by Penicillium decumbens naringinase.
TLDR
The results suggest that Q-3-G may be confirmed more effective and bioavailable food component than rutin and even quercetin because of its enhanced solubility and inhibitory properties. Expand
A spectrophotometric method for high-throughput screening of α-l-rhamnosidase activity on rutin coupled with a β-d-glucosidase assay
TLDR
The findings demonstrated that this novel spectrophotometric method coupled with the β-d-glucosidase assay might be applied for high-throughput screening of different α-l-rhamnosidases and a great number of mutants from semi-rational design and directed evolution for α- l-ramnosidase. Expand
Bioavailability is improved by enzymatic modification of the citrus flavonoid hesperidin in humans: a randomized, double-blind, crossover trial.
TLDR
The results of this study demonstrated that the bioavailability of hesperidin was modulated by enzymatic conversion to hesperetin-7-glucoside, thus changing the absorption site from the colon to the small intestine, which may affect future interventions concerning the health benefits of citrus flavonoids. Expand
α-l-Rhamnosidase: A review
TLDR
This review consists of a brief introduction of α- l -rhamnosidase which is followed by a critical description of the methods used for assaying the enzyme activity and the identification of areas which needs further extensive studies. Expand
Enzymatic de-glycosylation of rutin improves its antioxidant and antiproliferative activities.
TLDR
In vitro inhibitory activity against ten human tumor cell lines showed that hydrolyzed rutin exerted a more potent antiproliferative effect than quercetin and rut in on various cancer cell lines, specially glioma, and ovarian and breast adenocarcinomas, indicating that quercETin-3-glucoside could be a promising functional derivative obtained by r Rutin hydrolysis. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 22 REFERENCES
Quantification of anthocyanins in commercial black currant juices by simple high-performance liquid chromatography. Investigation of their pH stability and antioxidative potency.
TLDR
The antioxidant capacity of all 13 black currant juices was investigated by TEAC and FRAP, and the antioxidant potential of both the anthocyanin and the vitamin C contents in the juices was evaluated indicated that <70% of the antioxidants capacity of the juices could be attributed to the anthOCyanin content or to vitamin C, signifying that other very potent antioxidants are present in commercial blackCurrant juices. Expand
Strawberry anthocyanins are recovered in urine as glucuro- and sulfoconjugates in humans.
TLDR
It is demonstrated that anthocyanins were glucuro- and sulfo-conjugated in humans and that the main metabolite of strawberry anthocianins in human urine was a monoglucuronide of pelargonidin. Expand
Purification and Characterization of Two Different α-l-Rhamnosidases, RhaA and RhaB, fromAspergillus aculeatus
ABSTRACT Two proteins exhibiting α-l-rhamnosidase activity, RhaA and RhaB, were identified upon fractionation and purification of a culture filtrate from Aspergillus aculeatus grown on hesperidin.Expand
Quercetin 3-O-β-glucoside is better absorbed than other quercetin forms and is not present in rat plasma
TLDR
The result suggests that quercetin 3-O-β-glucoside is hydrolysed before or during its intestinal absorption, whereas the binding of a rhamnose to the aglycone markedly depresses it. Expand
Varietal differences among the polyphenol profiles of seven table grape cultivars studied by LC-DAD-MS-MS.
TLDR
The results indicate that the intake of unpeeled table grapes should be recommended in dietary habits as a potential source of antioxidant and anticarcinogenic phenolic compounds. Expand
Bioavailablility of elderberry anthocyanins
TLDR
The current findings appear to refute assumptions that anthocyanins are not absorbed in their unchanged glycosylated forms in humans, and suggest the consumption of diets rich in fruits and vegetables and a decreased risk of cardiovascular disease and cancers. Expand
Flavonol Glycoside Content and Composition of Tea Infusions Made from Commercially Available Teas and Tea Products
The composition and content of flavonol glycosides (FGs) have been measured in infusions of a range of black tea and black tea products. Tea contains a mixture of glycosides of quercetin, kaempferol,Expand
The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man.
TLDR
It is suggested that quercetin glucoside is actively absorbed from the small intestine, whereas quercettin rutinoside is absorbed fromThe colon after deglycosylation, suggesting that Absorption of other food components might also be enhanced by attachment of a glucose group. Expand
Effect of Processing Techniques at Industrial Scale on Orange Juice Antioxidant and Beneficial Health Compounds
Phenolic compounds, vitamin C (L-ascorbic acid and L-dehydroascorbic acid), and antioxidant capacity were evaluated in orange juices manufactured by different techniques. Five processes at industrialExpand
Metabolism of apigenin by rat liver phase I and phase ii enzymes and by isolated perfused rat liver.
TLDR
New data is provided about the metabolism of apigenin and the interest value of using various experimental models in metabolic studies is shown. Expand
...
1
2
3
...