Production of antibodies against mouse immune T (type II) interferon and their neutralizing properties.

@article{Stefanos1980ProductionOA,
  title={Production of antibodies against mouse immune T (type II) interferon and their neutralizing properties.},
  author={S Stefanos and L Catinot and Juana Wietzerbin and E T Falcoff},
  journal={The Journal of general virology},
  year={1980},
  volume={50 1},
  pages={225-9}
}
An antiserum to immune T-type mouse interferon was prepared in rabbits by repeated injections of interferon, induced by phytohaemagglutinin (PHA) in mouse spleen cells and purified to 1 X 10(5) units/mg protein. The antiserum neutralized mouse interferons synthesized in vitro in response to several T mitogens and Brucella organisms, and also the type II interferon present in the serum of BCG-sensitized mice after an injection of the specific antigen, tuberculin. All these interferons are thus… CONTINUE READING

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