Production of alpha-fetoprotein by cultured rat ascites hepatoma cells determined in vivo as alpha-fetoprotein-negative.

@article{Isaka1977ProductionOA,
  title={Production of alpha-fetoprotein by cultured rat ascites hepatoma cells determined in vivo as alpha-fetoprotein-negative.},
  author={Hirotsugu Isaka and Minako Koura and S Koura and Hiroe Yoshii and M Hattanmaru},
  journal={Gan},
  year={1977},
  volume={68 3},
  pages={363-7}
}
Three ascites hepatoma cells of the rat, AH-41B, AH-34, and AH-64B, which had been determined in vivo as alpha-fetoprotein-negative, were cultivated in vitro in a medium containing adenosine 3',5'-cyclic monophosphate (cyclic AMP), cyclic dibutyryl-AMP, or theophylline. The concentration of alpha-fetoprotein in culture media was measured by the 125 I… CONTINUE READING