Production of a soluble gammadelta T-cell receptor to identify ligands for the murine intestinal intraepithelial gammadelta T cell population.


Although the functions and antigen recognition requirements of alphabeta T cells are well characterised, the antigens recognised by gammadelta T cells and the consequences of this recognition are unclear. gammadelta T cells are enriched within epithelia, where they eradicate transformed epithelial cells and regulate inflammation. To understand how this… (More)