Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species.

@article{Engelhardt2010ProductionOA,
  title={Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species.},
  author={Kerstin Engelhardt and Kristin F. Degnes and Michael Kemmler and Harald Bredholt and Espen Fjaervik and Geir Klinkenberg and H{\aa}vard Sletta and Trond E. Ellingsen and Sergey B Zotchev},
  journal={Applied and environmental microbiology},
  year={2010},
  volume={76 15},
  pages={
          4969-76
        }
}
Twenty-seven marine sediment- and sponge-derived actinomycetes with a preference for or dependence on seawater for growth were classified at the genus level using molecular taxonomy. Their potential to produce bioactive secondary metabolites was analyzed by PCR screening for genes involved in polyketide and nonribosomal peptide antibiotic synthesis. Using microwell cultures, conditions for the production of antibacterial and antifungal compounds were identified for 15 of the 27 isolates… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 59 CITATIONS, ESTIMATED 86% COVERAGE

Analysis of the biosynthesis of antibacterial cyclic dipeptides in Nocardiopsis alba

  • Archives of Microbiology
  • 2014
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Natural thiopeptides as a privileged scaffold for drug discovery and therapeutic development

Xiaoqi Shen, Muhammad Mustafa, Yanyang Chen, Yingying Cao, Jiangtao Gao
  • Medicinal Chemistry Research
  • 2019
VIEW 2 EXCERPTS
CITES BACKGROUND

THE BIOTECHNOLOGICAL POTENTIAL OF SECONDARY METABOLITES FROM MARINE BACTERIA

Boris Andryukov, Valery Mikhailov, Nataly Besednova
  • 2019

FILTER CITATIONS BY YEAR

2010
2019

CITATION STATISTICS

  • 7 Highly Influenced Citations

  • Averaged 5 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 44 REFERENCES