Production of a monoclonal antibody useful in the molecular characterization of murine T-cell-replacing factor/B-cell growth factor II.

@article{Harada1987ProductionOA,
  title={Production of a monoclonal antibody useful in the molecular characterization of murine T-cell-replacing factor/B-cell growth factor II.},
  author={Nobuyuki Harada and Toshitada Takahashi and Mitsuhiro Matsumoto and Tatsuo Kinashi and J Ohara and Yuji Kikuchi and N Koyama and Eva Severinson and Yoshio Yaoita and T. Honjo},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 13},
  pages={4581-5}
}
T-cell-replacing factor (TRF) is a T-cell-derived factor required for terminal differentiation of activated B cells to immunoglobulin-secreting cells. Previous studies have shown that a murine T-cell hybrid (B151K12) produces factor(s) that (i) induce immunoglobulin secretion by the B-cell leukemia line BCL1 and secondary anti-2,4-dinitrophenyl IgG synthesis in vitro by dinitrophenyl-primed B cells (TRF activity) and (ii) cause proliferation of the BCL1 cells [B-cell growth factor II (BCGF-II… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Interleukin-5 and IL-5 receptor in health and diseases

Proceedings of the Japan Academy. Series B, Physical and biological sciences • 2011

Similar Papers

Loading similar papers…