Production of a Polysaccharide by Staphylococcus aureus. I. Enhancement by Penicillins

@article{Warren1963ProductionOA,
  title={Production of a Polysaccharide by Staphylococcus aureus. I. Enhancement by Penicillins},
  author={George H. Warren and Julia H. Gray},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  year={1963},
  volume={113},
  pages={251 - 255}
}
Summary A polysaccharide has been isolated from heat-treated or sonically disrupted cells of S. aureus. The polysaccharide is readily attacked by bovine testicular but not by bacterial hyaluronidase. Under the influence of subinhibitory concentrations of penicillin G and nafcillin, the production of the polysaccharide is greatly increased. The possible influence of penicillin on a fundamental pathway or enzyme system involved in the breakdown of the polysaccharide is discussed. 

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Antimicrobiul Agents and Chemotherapy

S. B. Rosenman, G. H. Warren
  • Am. SOC. Microb.,
  • 1962