Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis.

@article{Geisenberger2000ProductionON,
  title={Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis.},
  author={O Geisenberger and Michael C Givskov and Kathrin Riedel and Niels H\oiby and Burkhard T{\"u}mmler and Leo Eberl},
  journal={FEMS microbiology letters},
  year={2000},
  volume={184 2},
  pages={
          273-8
        }
}
The N-acyl-L-homoserine lactones (AHLs) produced by sequential Pseudomonas aeruginosa isolates from chronically infected patients with cystic fibrosis were analyzed by thin-layer chromatography. It is demonstrated that both the amounts and the types of molecules synthesized by isolates from patients who were monitored over periods of up to 11 years do not change significantly during chronic colonization. However, in the case of a patient who became co-infected with an AHL-producing Burkholderia… CONTINUE READING

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