Production of Human Endothelial Cells Free from Soluble Xenogeneic Antigens for Bioartificial Small Diameter Vascular Graft Endothelization

@inproceedings{Carvalho2015ProductionOH,
  title={Production of Human Endothelial Cells Free from Soluble Xenogeneic Antigens for Bioartificial Small Diameter Vascular Graft Endothelization},
  author={Juliana Lott de Carvalho and Alessandra Zonari and Ana Cl{\'a}udia Chagas de Paula and Thais Maria Martins and Dawidson Assis Gomes and Alfredo de Miranda G{\'o}es},
  booktitle={BioMed research international},
  year={2015}
}
Arterial bypass graft implantation remains the primary therapy for patients with advanced cardiovascular disease, but most lack adequate saphenous vein or other conduits for bypass procedures and would benefit from a bioartificial conduit. This study aimed to produce human endothelial cells (hECs) in large scale, free from xenogeneic antigens, to develop a small diameter, compatible vessel for potential use as a vascular graft. Human adipose-derived stromal cells (hASCs) were isolated, cultured… CONTINUE READING
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