Production of Angiotensin-I Converting Enzyme Inhibitory Hydrolysates from Egg Albumen

@inproceedings{Kim2003ProductionOA,
  title={Production of Angiotensin-I Converting Enzyme Inhibitory Hydrolysates from Egg Albumen},
  author={Hye-Sun Kim and Jun Sang Ham and Seok Geun Jeong and Yeong Min Yoo and Hee Sun Chae and C. N. Ahn and Jung Moo Lee},
  year={2003}
}
ACE (Angiotensin-I converting enzyme) inhibitory peptides derived from foods are thought to suppress high blood pressure by inhibiting ACE. We tried to make efficient production of the ACE inhibitory hydrolysate from egg albumen. A hydrolysate digested by neutrase presented the highest ACE inhibitory activity (IC50 value=256.35 µg/ml) and the proper proteolysis was occurred by 1.0% enzyme addition and 4 h incubation at 47°C. Antihypertensive effect of neutrase hydrolysate was investigated in… CONTINUE READING

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