Production of Alkaline Protease with Teredinobacter turnirae in Controlled Fed-batch Fermentation

  title={Production of Alkaline Protease with Teredinobacter turnirae in Controlled Fed-batch Fermentation},
  author={Usama I Beshay and Ant{\'o}nio Moreira},
  journal={Biotechnology Letters},
By using our previously optimized media and a fed-batch operation controlled by LabVIEW Software, the key parameter for a high production of alkaline protease using the marine bacterium, Teredinobacter turnirae, was to maintain a low concentration of C and N-sources ( < 2 g sucrose l−1 and < 0.2 g NH4C l  l−1) using an appropriate fed-batch culture system. A maximum protease activity of 8250 U ml−1 was thus achieved. 

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