Production in Escherichia of moricin, a novel type antibacterial peptide from the silkworm, Bombyx mori.

@article{Hara1996ProductionIE,
  title={Production in Escherichia of moricin, a novel type antibacterial peptide from the silkworm, Bombyx mori.},
  author={Seiichi Hara and Minoru Yamakawa},
  journal={Biochemical and biophysical research communications},
  year={1996},
  volume={220 3},
  pages={664-9}
}
Moricin is a novel type antibacterial peptide recently isolated from the silkworm, Bombyx mori. Two foreign gene expression systems in Escherichia coli were employed to obtain a large amount of the peptide for further characterization. An artificial moricin gene was chemically synthesized and inserted into two expression vectors, pXa1 and pMAL-c2. The recombinant moricin was efficiently produced in E. coli as fusion proteins and released by chemical cleavage with cyanogen bromide or o… CONTINUE READING