Production in B. subtilis of hepatitis B core antigen and of major antigen of foot and mouth disease virus


Although Escherichia coli has generally been used as the host for expressing cloned genes, there may be advantages in using other bacteria, such as Bacillus subtilis, for making viral or eukaryotic polypeptides. B. subtilis is a non-pathogenic Grampositive bacterium which, unlike E. coli, does not produce endotoxins and excretes several extracellular… (More)
DOI: 10.1038/293481a0


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