Production and traffic of B lymphocytes in the extracortical central area of the guinea pig thymus.

@article{Baak1978ProductionAT,
  title={Production and traffic of B lymphocytes in the extracortical central area of the guinea pig thymus.},
  author={J. Pa Baak and Chris J L M Meijer and Rik J. Scheper and R Mullink and Louis Kater},
  journal={International archives of allergy and applied immunology},
  year={1978},
  volume={56 5},
  pages={424-34}
}
Lymphocytes in the stroma and lymphatics of the extra-cortical central area (ECCA) of the guinea pig thymus have been studied with light microscopy, quantitative microscopy, colchicin-induced mitotic arrest, EA (IgG) and EA (IgM) C adherence, surface immunoglobulins (Ig total, IgM, IgG), alkaline phosphatase activity and the effect of cyclophosphamide administration. The results suggest, that AP-positive, SIg-positive EAC-negative lymphocytes in the ECCA proliferate and maturate into AP… CONTINUE READING