Production and disposal of medium-chain fatty acids in children with medium-chain acyl-CoA dehydrogenase deficiency

@article{Heales1994ProductionAD,
  title={Production and disposal of medium-chain fatty acids in children with medium-chain acyl-CoA dehydrogenase deficiency},
  author={Simon J. R. Heales and Geoffrey N Thompson and Amani Massoud and Shamima Rahman and David F. Halliday and James V. Leonard},
  journal={Journal of Inherited Metabolic Disease},
  year={1994},
  volume={17},
  pages={74-80}
}
The effect of fasting on plasma concentrations of fatty acids has been determined in four children with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. In addition, thein vivo rate of octanoate oxidation was measured, using [1-13C]octanoate. In the three older children (1.5–11.2 years), fasting for up to 18 h stimulated lipolysis, as reflected by the increasing concentration of free fatty acids, but with little rise in concentrations of medium-chain fatty acids, octanoate, decanoate… CONTINUE READING
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