Production and characterization of antioxidant apigenin nanocrystals as a novel UV skin protective formulation.


Flavonoids have many positive effects on various cell layers of the skin (e.g. anti-oxidant, anti-allergic and anti-inflammatory effects). However, the limiting factor of the use of flavonoids is their low water solubility. To overcome the poor solubility, apigenin nanosuspensions were prepared using the combination technology (CT), i.e. bead milling and… (More)
DOI: 10.1016/j.ijpharm.2011.08.018