Production and characterization of an allergen panel for component-resolved diagnosis of celery allergy.

@article{Bublin2008ProductionAC,
  title={Production and characterization of an allergen panel for component-resolved diagnosis of celery allergy.},
  author={Merima Bublin and Iris Lauer and Christina Nieto Oberhuber and Stefano Alessandri and Peter Briza and C Radauer and Martin Himly and Heimo Breiteneder and Stefan Vieths and Karin Hoffmann-Sommergruber},
  journal={Molecular nutrition & food research},
  year={2008},
  volume={52 Suppl 2},
  pages={S241-50}
}
In celery a relevant food allergen source, three allergens have been identified so far: Api g 1 and Api g 4, and one glycosylated protein, Api g 5. For component-resolved food allergy diagnosis high amounts of well-defined allergens are needed. Depending on the individual celery allergen, protocols for heterologous production and purification from natural source, respectively, were established to obtain homogenous protein batches. Afterwards the purified recombinant allergens, Api g 1, Api g 4… CONTINUE READING

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