Production and Quality Control of 166 Ho-Chitosan for Therapeutic Applications

@inproceedings{Zolghadri2010ProductionAQ,
  title={Production and Quality Control of 166 Ho-Chitosan for Therapeutic Applications},
  author={Samaneh Zolghadri and Amir Reza Jalilian and Hassan Yousefnia and Ali Bahrami-Samani and Simindokht Shirvani-Arani and Mohammad Sh. Mazidi and Mehdi M. Akhlaghi and Mohammad Ghannadi-Maragheh},
  year={2010}
}
Introduction: In this research, [Ho]Holmium chitosan complex production is described in details, followed by determination of complex radiochemical purity, stability and biodistribution (after intra-articular injection) in wild-type male rats. Finally a Ho-166 based chitosan kit for ultimate radiosynovectomy as well as radiotherapy applications was developed. Methods: Ho-chitosan complex was prepared using chitosan concentrations and HoCl3 followed by intraarticular injection and… CONTINUE READING

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