Production, purification, sequencing and activity spectra of mutacins D-123.1 and F-59.1

@inproceedings{Nicolas2010ProductionPS,
  title={Production, purification, sequencing and activity spectra of mutacins D-123.1 and F-59.1},
  author={Guillaume G. Nicolas and Gis{\`e}le Lapointe and M. C. Lavoie},
  booktitle={BMC Microbiology},
  year={2010}
}
The increase in bacterial resistance to antibiotics impels the development of new anti-bacterial substances. Mutacins (bacteriocins) are small antibacterial peptides produced by Streptococcus mutans showing activity against bacterial pathogens. The objective of the study was to produce and characterise additional mutacins in order to find new useful antibacterial substances. Mutacin F-59.1 was produced in liquid media by S. mutans 59.1 while production of mutacin D-123.1 by S. mutans 123.1 was… CONTINUE READING