Producing functional recombinant human keratinocyte growth factor in Pichia pastoris and investigating its protective role against irradiation.

@article{Bahadori2018ProducingFR,
  title={Producing functional recombinant human keratinocyte growth factor in Pichia pastoris and investigating its protective role against irradiation.},
  author={Zahra Bahadori and Hamid Reza Kalhor and Seyed Javad Mowla},
  journal={Enzyme and microbial technology},
  year={2018},
  volume={111},
  pages={
          12-20
        }
}
  • Zahra Bahadori, Hamid Reza Kalhor, Seyed Javad Mowla
  • Published in
    Enzyme and microbial…
    2018
  • Medicine, Chemistry
  • Keratinocyte Growth Factor (KGF) is a paracrine-acting, epithelial mitogen that plays a prominent role in the regeneration of damaged epithelial tissues. In spite of different attempts to produce recombinant human KGF in many organisms, including bacteria, mammalian cells, plant cells and insect cells; production of recombinant form suffers from lower yields and recovery relative to other recombinant proteins of similar size and properties. Due to many advantages of Pichia pastoris expression… CONTINUE READING

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