Producing PPARgamma2 knockdown in mouse liver.


A high saturated fat diet induces fatty liver in mice. The fatty liver is triggered initially by an increase in PPARγ2 protein in the liver, which leads to increased expression of lipogenic genes. Inactivation of PPARγ2 may improve fatty liver induced by a high saturated fat diet. RNA interference of PPARγ2 should be a powerful tool to elucidate the role of… (More)
DOI: 10.1007/978-1-62703-155-4_7


Cite this paper

@article{Yamazaki2013ProducingPK, title={Producing PPARgamma2 knockdown in mouse liver.}, author={Tomomi Yamazaki and Osamu Ezaki}, journal={Methods in molecular biology}, year={2013}, volume={952}, pages={99-116} }