Prodrug designing of NSAIDs.

@article{Halen2009ProdrugDO,
  title={Prodrug designing of NSAIDs.},
  author={Parmeshwari Kuldeep Kumar Halen and Prashant Revan Murumkar and Rajani Giridhar and Mange Ram Yadav},
  journal={Mini reviews in medicinal chemistry},
  year={2009},
  volume={9 1},
  pages={124-39}
}
Non-steroidal anti-inflammatory drugs (NSAIDs), commonly used for the treatment of chronic inflammatory diseases suffer from several undesired side effects, the most important being gastrointestinal (GI) irritation and ulceration. The prodrug designing is one of the several strategies used to overcome this drawback. The rationale behind the prodrug concept… CONTINUE READING