Prodrug-based nanoparticulate drug delivery strategies for cancer therapy.

  title={Prodrug-based nanoparticulate drug delivery strategies for cancer therapy.},
  author={Cong Luo and Jin Sun and Bingjun Sun and Zhonggui He},
  journal={Trends in pharmacological sciences},
  volume={35 11},
Despite the rapid developments in nanotechnology and biomaterials, the efficient delivery of chemotherapeutic agents is still challenging. Prodrug-based nanoassemblies have many advantages as a potent platform for anticancer drug delivery, such as improved drug availability, high drug loading efficiency, resistance to recrystallization upon encapsulation, and spatially and temporally controllable drug release. In this review, we discuss prodrug-based nanocarriers for cancer therapy, including… CONTINUE READING
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