Procyanidins from grape pomace are suitable inhibitors of human endothelial NADPH oxidase.

@article{lvarez2012ProcyanidinsFG,
  title={Procyanidins from grape pomace are suitable inhibitors of human endothelial NADPH oxidase.},
  author={Ezequiel {\'A}lvarez and Bruno K Rodi{\~n}o-Janeiro and Mar{\'i}a Jos{\'e} Jerez and Rafael Ucieda-Somoza and Mar{\'i}a Jos{\'e} N{\'u}{\~n}ez and Jos{\'e} Ram{\'o}n G{\'o}nzalez-Juanatey},
  journal={Journal of cellular biochemistry},
  year={2012},
  volume={113 4},
  pages={1386-96}
}
Procyanidins have been associated with a reduced risk of cardiovascular diseases such as atherosclerosis. However, the molecular mechanisms underlying this benefit are not fully understood. Increased reactive oxygen species (ROS) production generated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is a common problem in different cardiovascular diseases. Our objective was to evaluate the effects of procyanidin-rich fractions from distilled grape pomace on NADPH oxidase activity… CONTINUE READING
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