Proconvulsant effect of post-weaning social isolation stress may be associated with dysregulation of opioid system in the male mice.


Opioid system has been reported to be involved in the consequences of post-weaning social isolation stress (SIS) such as hypoalgesia and social behaviors. Also, previous studies have shown that SIS increases mu opioid receptor expression in the regions of the brain associated with epileptogenesis such as basolateral amygdala and cortex. Interestingly… (More)
DOI: 10.1016/j.mehy.2015.01.041


  • Presentations referencing similar topics