Procoagulant activity of endotoxin-treated human endothelial cells exposed to native human flowing blood.

@article{Clozel1989ProcoagulantAO,
  title={Procoagulant activity of endotoxin-treated human endothelial cells exposed to native human flowing blood.},
  author={Martine Clozel and Hartmut Kuhn and Hans Rudolf Baumgartner},
  journal={Blood},
  year={1989},
  volume={73 3},
  pages={
          729-33
        }
}
It has been reported that cultured endothelial cells become procoagulant when exposed to endotoxin. This prompted us to investigate whether human endothelial cells treated with endotoxin could promote the generation of fibrin when exposed to human flowing blood. For this purpose we used a parallel-plate perfusion chamber in which confluent cultured endothelial cells from human umbilical veins were exposed for five minutes to directly drawn human nonanticoagulated blood, at wall shear rates of… CONTINUE READING

Similar Papers

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Fibrinogen, fibrin and factor XIII, in Zwaal RFA, Hemker HC (eds): Blood Coagulation, Elsevier

A Henschen, J McDonagh
  • Science Publishers,
  • 1986

Fibrinogen, fibrin and factor XIII, in Zwaal RFA, Hemker HC (eds): Blood Coagulation, Elsevier

A Henschen, J McDonagh
  • Science Publishers,
  • 1986