Processing of nux vomica. VII. Antinociceptive effects of crude alkaloids from the processed and unprocessed seeds of Strychnos nux-vomica in mice.

@article{Cai1996ProcessingON,
  title={Processing of nux vomica. VII. Antinociceptive effects of crude alkaloids from the processed and unprocessed seeds of Strychnos nux-vomica in mice.},
  author={Ben-qin Cai and Tetsuro Nagasawa and Shigetoshi Kadota and Masao Hattori and Takashi Namba and Yasushi Kuraishi},
  journal={Biological & pharmaceutical bulletin},
  year={1996},
  volume={19 1},
  pages={
          127-31
        }
}
We examined the antinociceptive effects of the crude alkaloid fractions (CAF) of nux vomica (the dried seeds of Strychnos nux-vomica L.) and the influences of various processing methods upon their antinociception in three analgesic tests in mice. In the tail-pressure test, the CAF (0.01--1 micrograms/kg, i.p.) of nux vomica that was unprocessed or treated with sand-, licorice-, oil- or vinegar and sand-processing showed clear antinociception. The CAF (1 microgram/kg, i.p.) of vinegar-processed… CONTINUE READING

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