• DOI:10.1248/CPB.38.1295
Corpus ID: 40460397

Processing of nux vomica. II. Changes in alkaloid composition of the seeds of Strychnos nux-vomica on traditional drug-processing.

@article{Cai1990ProcessingON,
  title={Processing of nux vomica. II. Changes in alkaloid composition of the seeds of Strychnos nux-vomica on traditional drug-processing.},
  author={B. Cai and M. Hattori and T. Namba},
  journal={Chemical & pharmaceutical bulletin},
  year={1990},
  volume={38 5},
  pages={
          1295-8
        }
}

B. Cai, M. Hattori, T. Namba

Published 1990

Chemistry, Medicine

Chemical & pharmaceutical bulletin

In the course of our study on the drug-processing of the seeds of Strychnos nux-vomica L. (Loganiaceae), the alkaloid composition of the heat-treated seeds of S. nux-vomica was compared to that of the untreated seeds. On heat treatment, the contents of the major alkaloids such as strychnine and brucine declined significantly with increases in the amounts of isostrychnine, isobrucine, strychnine N-oxide and brucine N-oxide. The cleavage of an ether linkage and the occurrence of N-oxidation were… CONTINUE READING

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