Processing and major histocompatibility complex class II presentation of Legionella pneumophila antigens by infected macrophages.

Abstract

To better understand interactions between the intracellular pathogen Legionella pneumophila and macrophages (Mphis), host and bacterial determinants important for presentation of antigens on major histocompatibility complex class II molecules (MHC-II) were investigated. It was determined that immune CD4 T-cell responses to murine bone marrow-derived Mphis… (More)

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