Processing, Distribution, and Function of VGF, a Neuronal and Endocrine Peptide Precursor

@article{Levi2004ProcessingDA,
  title={Processing, Distribution, and Function of VGF, a Neuronal and Endocrine Peptide Precursor},
  author={Andrea Levi and Gian-Luca Ferri and Elizabeth Watson and Roberta Possenti and Stephen R J Salton},
  journal={Cellular and Molecular Neurobiology},
  year={2004},
  volume={24},
  pages={517-533}
}
1. The vgf gene encodes a neuropeptide precursor with a restricted pattern of expression that is limited to a subset of neurons in the central and peripheral nervous systems and to specific populations of endocrine cells in the adenohypophysis, adrenal medulla, gastrointestinal tract, and pancreas. In responsive neurons, vgf transcription is upregulated by neurotrophins, the basis for the original identification of VGF as nerve growth factor- (NGF) inducible in PC12 cells (A. Levi, J. D… CONTINUE READING