Proceedings: Testicular feminization: studies of the molecular basis of a genetic defect.

@article{Bardin1974ProceedingsTF,
  title={Proceedings: Testicular feminization: studies of the molecular basis of a genetic defect.},
  author={C. Bardin and L. Bullock},
  journal={The Journal of investigative dermatology},
  year={1974},
  volume={63 1},
  pages={
          75-84
        }
}
Testicular feminization is an inherited disorder which is transmitted by some women to half their male offspring. The affected individuals are genetic males with end organ insensitivity to endogenous and exogenous androgens. As a consequence, they lack androgen-dependent differentiation and present clinically as phenotypic females with primary amenorrhea. Testicular feminization has also been described in the rat and the mouse. Studies on these rodents indicate that a major tissue abnormality… Expand
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Microscopic epididymides in testicular feminisation
  • 12
Evaluation of the involvement of the androgen receptor in motivated behaviour using male rats carrying the testicular feminization mutation
  • PDF
Stromal Influence on Expression of Morphological and Functional Characteristics of Urogenital Epithelia
  • 7
Specific 5α‐dihydrotestosterone binding in labial skin fibroblasts c1ultured from patients with male pseudohermaphroditism
  • 11
The Role of Receptors in the Anabolic Action of Androgens
  • 20
The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wild-type and androgen-insensitive (Tfm) mice.
  • 275
Fine structure of submandibular glands of mice with testicular feminization (Tfm/Y)
  • 13
Testicular feminization syndrome: current clinical considerations.
  • 7
Putative androgen receptors distinguished in wild-type and testicular-feminized (Tfm) mice
  • 51
Male pseudohermaphroditism: Genetics and Clinical delineation
  • 14
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