Procedure for the quantitative evaluation of motor disturbances in cerebellar ataxic patients

@article{Ferrarin2006ProcedureFT,
  title={Procedure for the quantitative evaluation of motor disturbances in cerebellar ataxic patients},
  author={Maurizio Ferrarin and Maira Gironi and Laura Mendozzi and Raffaello Nemni and Paolo Mazzoleni and Marco Rabuffetti},
  journal={Medical and Biological Engineering and Computing},
  year={2006},
  volume={43},
  pages={349-356}
}
Cerebellar ataxia is a complex motor disturbance that involves the planning and execution of movements and reduces movement accuracy and co-ordination. The quantification of ataxic signs is commonly realised through visual examination of motor tasks performed by the patient and assignment of scores to specific items composing the international co-operative ataxia rating scale (ICARS). The present work studied an experimental procedure to characterise specific aspects of motor disturbances in… 
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References

SHOWING 1-10 OF 31 REFERENCES
Target board test for the quantification of ataxia in tremulous patients
TLDR
The TBT provides simple quantitative objective measurements of upper limb ataxia and measuring Dysmetria in the presence of tremor, and correlated significantly with dysmetria, dysdiadochokinesia, kinetic tremor and (inversely) with the finger-tapping test.
Measuring ataxia: quantification based on the standard neurological examination.
TLDR
Results indicate that tests 1, 2 and 4 are sensitive for the detection of ataxia and of changes in its severity and that the test-retest repeatability was excellent.
Bradykinesia akinesia inco-ordination test (BRAIN TEST): an objective computerised assessment of upper limb motor function
TLDR
The BRAIN test assesses speed, accuracy, and rhythmicity of upper limb movements regardless of their physiological basis and correlate well with clinical rating scales in Parkinson’s disease and cerebellar dysfunction.
International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome
TLDR
The scale proposed involves a compartimentalized quantification of postural and stance disorders, limb ataxia, dysarthria and oculomotor disorders, in order that a subscore concerning these symptoms may be separately studied.
Gait in patients with cerebellar ataxia
TLDR
The gait pattern of patients with cerebellar degeneration shows incoordination similar to that previously described for their multijoint limb motion.
Typical features of cerebellar ataxic gait
TLDR
Typical features of gait in CD are reduced cadence with increased balance related variables and an almost normal range of motion (with increased variability) in the joints of the lower extremity.
Cerebellar ataxia: quantitative assessment and cybernetic interpretation.
TLDR
A straightforward kinematic and kinetic analysis of reaching movements of patients with cerebellar ataxia in conjunction with a cybernetic interpretation of the data is proposed to capture key deficits in the underlying motor control processes.
Comparative analysis of gait in Parkinson's disease, cerebellar ataxia and subcortical arteriosclerotic encephalopathy.
TLDR
Whereas the findings in patients with Parkinson's disease can be explained as a reduction of force gain, the observations for patients with ataxia and subcortical arteriosclerotic encephalopathy reflect an altered spatiotemporal gait strategy in order to compensate for instability.
Characteristics of parkinsonian and ataxic gaits: a study using surface electromyograms, angular displacements and floor reaction forces
TLDR
Measurement of EMG for each phase revealed disease-specific factors, and that of DeltaEMG/Deltaangle might be a conventional clue for estimation of reflexes for these gait disorders.
Kinetic tremor in a reach‐to‐grasp movement in Parkinson's disease
TLDR
The authors' results confirm similarities between the tremor at rest and the oscillations during a sustained postural task in classic parkinsonian tremor, which seems to be generated by basal ganglia oscillators.
...
1
2
3
4
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