Procedural pain and brain development in premature newborns.

  title={Procedural pain and brain development in premature newborns.},
  author={Susanne Brummelte and Ruth E. Grunau and Vann Chau and Kenneth J. Poskitt and Rollin Brant and Jillian Vinall and Ayala Gover and Anne R Synnes and Steven Paul Miller},
  journal={Annals of neurology},
  volume={71 3},
OBJECTIVE Preterm infants are exposed to multiple painful procedures in the neonatal intensive care unit (NICU) during a period of rapid brain development. Our aim was to examine relationships between procedural pain in the NICU and early brain development in very preterm infants. METHODS Infants born very preterm (N=86; 24-32 weeks gestational age) were followed prospectively from birth, and studied with magnetic resonance imaging, 3-dimensional magnetic resonance spectroscopic imaging, and… CONTINUE READING
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