Procalcitonin for antibiotic treatment in intensive care unit patients.

  title={Procalcitonin for antibiotic treatment in intensive care unit patients.},
  author={Nathalie Layios and Bernard C. Lambermont},
  journal={Current infectious disease reports},
  volume={15 5},
Procalcitonin (PCT), a 116-aminoacids prohormone, has been substantially studied over the last 2 decades in the field of sepsis. Disappointingly low sensitivity values led to the abandonment of the concept of it as a diagnostic tool and then to its being considered more as a prognostic marker with a good correlation with severe infection. Later on, growing concerns about multidrug-resistant bacteria in the ICU environment and about the cost and side effects of antibiotics suggested that PCT… CONTINUE READING